Publication portfolio

Research across the spectrum of neurodegeneration.

Biomarker discovery, systems biology, disease progression, metabolic comorbidity, lifestyle, and translational data science across Parkinson’s disease, Alzheimer’s disease, ALS, frontotemporal dementia, and atypical parkinsonian disorders.

Featured publications

Recent work

Select either publication image to open the article. The GLP-1 article links to its freely accessible PubMed record.

Trends in Molecular Medicine cover featuring a brain, blood biomarkers, DNA, and an injection device

Cover article · 2025

GLP-1 agonists in neurodegeneration: a multimodal biomarker-guided approach

Trends in Molecular Medicine. A framework for integrating multimodal biomarkers into the development and evaluation of GLP-1 receptor agonists across neurodegenerative diseases.

Free access on PubMed ↗Cell Press ↗

Graphical overview of diabetes-related mechanisms contributing to ALS, Alzheimer’s disease, and Parkinson’s disease

Review · 2023

Diabetes: a tipping point in neurodegenerative diseases

Trends in Molecular Medicine. An analysis of convergent metabolic, vascular, inflammatory, and molecular mechanisms linking type 2 diabetes with neurodegenerative disease.

Read at Cell Press ↗DOI ↗

Complete record

Peer-reviewed publications

2026
Baseline clinical features outperform structural MRI in predicting rapid cognitive and motor decline in Parkinson’s diseasenpj Parkinson’s Disease · In press
2023
Diet and lifestyle impact the development and progression of Alzheimer’s dementiaFrontiers in Nutrition
2023
Biological and clinical implications of sex-specific differences in Alzheimer’s diseaseHandbook of Experimental Pharmacology · Book chapter
2023
Physical activity and lifestyle modifications in the treatment of neurodegenerative diseasesFrontiers in Aging Neuroscience
2023
Coexpression network analysis identifies molecular determinants of loneliness associated with neuropsychiatric and neurodegenerative diseasesInternational Journal of Molecular Sciences
2022
Sex-specific transcriptional rewiring in the brain of Alzheimer’s disease patientsFrontiers in Aging Neuroscience
2022
Physical activity rewires the human brain against neurodegenerationInternational Journal of Molecular Sciences
2022
Key disease mechanisms linked to amyotrophic lateral sclerosis in spinal cord motor neuronsFrontiers in Molecular Neuroscience
2021
Transcriptomic and network meta-analysis of frontotemporal dementiasFrontiers in Molecular Neuroscience
2021
Network analysis identifies sex-specific gene expression changes in blood of amyotrophic lateral sclerosis patientsInternational Journal of Molecular Sciences
2021
The impact of disease comorbidities in Alzheimer’s diseaseFrontiers in Aging Neuroscience
2020
Bioinformatic analysis reveals phosphodiesterase 4D-interacting protein as a key frontal cortex dementia switch geneInternational Journal of Molecular Sciences
2020
Transcriptomic and network analysis identifies shared and unique pathways across dementia spectrum disordersInternational Journal of Molecular Sciences
2019
Transcriptomic and network analysis highlight the association of diabetes at different stages of Alzheimer’s diseaseFrontiers in Neuroscience
2019
Computational identification of key genes that may regulate gene expression reprogramming in Alzheimer’s patientsPLOS ONE
2018
PTPRC expression in blood is downregulated in Parkinson’s and progressive supranuclear palsy disordersJournal of Parkinson’s Disease
2018
Evaluation of RNA blood biomarkers in the Parkinson’s Disease Biomarker ProgramFrontiers in Aging Neuroscience
2017
Biological and clinical implications of comorbidities in Parkinson’s diseaseFrontiers in Aging Neuroscience
2017
Evaluation of RNA blood biomarkers in individuals potentially at risk of Parkinson’s diseaseJournal of Parkinson’s Disease
2017
Dissecting the molecular mechanisms of neurodegenerative diseases through network biologyFrontiers in Aging Neuroscience
2017
Blood transcriptomic meta-analysis identifies dysregulation of hemoglobin and iron metabolism in Parkinson’s diseaseFrontiers in Aging Neuroscience
2016
Integrative transcriptomic meta-analysis of Parkinson’s disease and depression identifies NAMPT as a potential blood biomarker for de novo Parkinson’s diseaseScientific Reports
2015
Blood biomarkers associated with cognitive decline in early-stage and drug-naive Parkinson’s disease patientsPLOS ONE
2015
HNF4A and PTBP1 expression in the brain of neurodegenerative diseasesProceedings of the National Academy of Sciences
2015
Blood biomarkers for Parkinson’s diseaseProceedings of the National Academy of Sciences
2015
Network-based meta-analysis identifies HNF4A and PTBP1 as longitudinally dynamic biomarkers for Parkinson’s diseaseProceedings of the National Academy of Sciences
2014
A network approach to clinical intervention in neurodegenerative diseasesTrends in Molecular Medicine
2014
Network analysis identifies SOD2 mRNA as a potential biomarker for Parkinson’s diseasePLOS ONE
2014
Current challenges towards the development of a blood test for Parkinson’s diseaseDiagnostics
2014
System-based approaches to decode the molecular links in Parkinson’s disease and diabetesNeurobiology of Disease
2014
A network approach to diagnostic biomarkers in progressive supranuclear palsyMovement Disorders
2014
The emerging role of nutrition in Parkinson’s diseaseFrontiers in Aging Neuroscience
2013
Integrative network analysis unveils convergent molecular pathways in Parkinson’s disease and diabetesPLOS ONE
2013
Shared dysregulated pathways lead to Parkinson’s disease and diabetesTrends in Molecular Medicine
2013
Specific splice variants are associated with Parkinson’s diseaseMovement Disorders
2012
Biosignatures for Parkinson’s disease and atypical parkinsonian disordersPLOS ONE

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